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Fixing thy mind on Me, thou shalt by My grace overcome all obstacles; but if from egoism thou wilt not hear Me, thou shalt perish.

With your mind on me, by my grace you will cross over every obstacle. But if out of ego you will not listen, you will be lost.

Krishna presents a choice. If Arjuna keeps his mind on him, he will cross every difficulty by Krishna's grace. But if, out of ego, he refuses to listen, he will come to ruin. The tone becomes urgent after the gentleness of the previous verses. The warning is not a threat but a description of consequences: acting from ego isolates one from the help available, while trust opens the way through obstacles.