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Greater is their trouble whose minds are set on the unmanifested; for the goal; the unmanifested, is very hard for the embodied to reach.

The struggle is greater for those whose minds are set on the unmanifest, for the goal of the unmanifest is hard for embodied beings to reach.

Krishna explains why he favours personal devotion for most people. Those whose minds are attached to the unmanifest face greater difficulty, because the unmanifest goal is hard for embodied beings to reach. Human beings live in bodies and think in forms; it is hard for them to hold the mind on what has no form at all. The verse is a statement about human nature rather than about the ultimate status of either path. It explains Krishna's earlier answer in terms of compassion and practicality.